跳轉至內容
Merck

DDR1

discoidin domain receptor tyrosine kinase 1

同義詞:
CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
物種:
UniProtKB ID:
基因 ID:
  • Human(780) Summary: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(12305) discoidin domain receptor family, member 1
  • Rat(25678) discoidin domain receptor tyrosine kinase 1
  • Horse(100050861) discoidin domain receptor tyrosine kinase 1
  • naked mole-rat(101699683) discoidin domain receptor tyrosine kinase 1
  • domestic guinea pig(100725492) discoidin domain receptor tyrosine kinase 1
  • sheep(101104279) discoidin domain receptor tyrosine kinase 1
  • cow(534092) discoidin domain receptor tyrosine kinase 1
  • domestic cat(101096728) discoidin domain receptor tyrosine kinase 1
  • dog(474832) discoidin domain receptor tyrosine kinase 1
  • Zebrafish(100007346) discoidin domain receptor family, member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

產品編號
描述
物種活性
應用
Anti-phospho-DDR1 (pTyr513) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot
Anti-DDR1 (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
bovine, dog, horse, human, monkey, pig
應用
immunohistochemistry

Proteins

產品編號
描述
物種
DDR1 (444-端),活性,GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human