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Merck

CYBB

cytochrome b-245, beta polypeptide

同義詞:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
物種:
UniProtKB ID:
基因 ID:
  • Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Mouse(13058) cytochrome b-245, beta polypeptide
  • Rat(66021) cytochrome b-245, beta polypeptide
  • cow(281112) cytochrome b-245, beta polypeptide
  • sheep(100036757) cytochrome b-245, beta polypeptide
  • Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
  • dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • chicken(418581) cytochrome b-245, beta polypeptide
  • Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)

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Antibodies

產品編號
描述
物種活性
應用
Anti-gp91-phox Antibody, Upstate®, from rabbit,
物種活性
human
應用
western blot
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rabbit, rat
應用
western blot
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
western blot

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human CYBB,
物種
human