CYBB
cytochrome b-245, beta polypeptide
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Human CYBB (1536), Mouse Cybb (13058), Rat Cybb (66021), cow CYBB (281112), sheep CYBB (100036757), Domestic Rabbit CYBB (100008801), dog CYBB (491825), chicken CYBB (418581), Zebrafish cybb (393386)
- Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
- Mouse(13058) cytochrome b-245, beta polypeptide
- Rat(66021) cytochrome b-245, beta polypeptide
- cow(281112) cytochrome b-245, beta polypeptide
- sheep(100036757) cytochrome b-245, beta polypeptide
- Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
- dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
- chicken(418581) cytochrome b-245, beta polypeptide
- Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
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Antibodies
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
human, mouse, rabbit, rat
western blot
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
western blot