跳轉至內容
Merck

CTSB

cathepsin B

同義詞:
APPS, CPSB
物種:
UniProtKB ID:
基因 ID:
  • Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13030) cathepsin B
  • Rat(64529) cathepsin B
  • domestic guinea pig(100714169) cathepsin B
  • naked mole-rat(101709008) cathepsin B
  • dog(486077) cathepsin B
  • Horse(100060963) cathepsin B
  • domestic cat(101084873) cathepsin B
  • cow(281105) cathepsin B
  • sheep(780470) cathepsin B
  • chicken(396329) cathepsin B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

產品編號
描述
物種活性
應用
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
物種活性
bovine, human, porcine
應用
Monoclonal Anti- Cathepsin B 小鼠抗, clone CB59-4B11, purified from hybridoma cell culture,
物種活性
human, rat
應用
ELISA
immunohistochemistry

western blot
Anti-Cathepsin B, from rabbit, purified by affinity chromatography,
物種活性
human, rat
應用
immunohistochemistry
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
Z-Leu-Leu-Leu-al, ≥90% (HPLC),
物種
human
钙蛋白酶抑制剂I, ≥97% (TLC), powder,
物種
human
MG-132(R), ≥95% (HPLC),
物種
human
N-氰基二乙基胺, 99%,
物種
human

Proteins

產品編號
描述
物種
组织蛋白酶B 来源于人类肝脏, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
物種
human
组织蛋白酶B,来源于人肝脏, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
物種
human
组织蛋白酶B 来源于牛脾脏, lyophilized powder, ≥10 units/mg protein,
物種
cow
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
物種
human
组织蛋白酶B 来源于人类胎盘, lyophilized powder, ≥5 units/mg protein,
物種
human

Small Molecule - Substrate

產品編號
描述
物種
Z-精氨酸-精氨酸-7-酰氨基-4-甲基香豆素 盐酸盐, ,
物種
mouse, human, rat