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Merck

CACNA2D1

calcium channel, voltage-dependent, alpha 2/delta subunit 1

同義詞:
CACNA2, CACNL2A, CCHL2A
物種:
UniProtKB ID:
基因 ID:
  • Human(781) Summary: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
  • Mouse(12293) calcium channel, voltage-dependent, alpha2/delta subunit 1
  • Rat(25399) calcium channel, voltage-dependent, alpha2/delta subunit 1
  • chicken(768444) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • domestic guinea pig(100728887) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • naked mole-rat(101708369) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • cow(282608) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • sheep(101123550) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • dog(610342) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • Domestic Rabbit(100009105) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • domestic cat(101099450) calcium channel, voltage-dependent, alpha 2/delta subunit 1

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Small Molecule - Allosteric Modulator

產品編號
描述
物種
加巴喷丁, United States Pharmacopeia (USP) Reference Standard,
物種
human
加巴喷丁标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
加巴喷丁标准液 CRM 溶液, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
加巴喷丁, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
普瑞巴林, European Pharmacopoeia (EP) Reference Standard,
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
非洛地平, solid,
物種
human
硝苯地平, ≥98% (HPLC), powder,
物種
rat, mouse, human
加巴喷丁, solid,
物種
human, rat
Terodiline hydrochloride, ≥98% (HPLC), solid,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-CACNA2D1 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot
Anti-Calcium Channel Antibody, Voltage Gated α 2/δ-1, L-type, Chemicon®, from rabbit,
物種活性
rat
應用
western blot
Anti-CACNA2D1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
Monoclonal Anti-Dihydropyridine Receptor (α2 Subunit) antibody produced in mouse, clone 20A, ascites fluid, buffered aqueous solution,
物種活性
guinea pig, mouse, rabbit, rat
應用
immunohistochemistry
western blot
Anti-Calcium Channel (α2/δ-1 Subunit) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物種活性
human, mouse, pig, rat
應用
western blot

Small Molecule - Blocker

產品編號
描述
物種
Isradipine, ≥98% (HPLC), solid,
物種
human
非洛地平, solid,
物種
human
硝苯地平, ≥98% (HPLC), powder,
物種
rat, mouse, human
苄普地尔 盐酸盐, powder,
物種
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
物種
human