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Merck

BAD

BCL2-associated agonist of cell death

同義詞:
BBC2, BCL2L8
物種:
UniProtKB ID:
基因 ID:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

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Small Molecule - Antagonist

產品編號
描述
物種
2,3-二羟基萘, ≥98.0% (HPLC),
物種
human
4-联苯乙酸, 98%,
物種
human
联苯-4-羧酸, 95%,
物種
human
(±)-棉酚 来源于棉花种子, ≥95% (HPLC),
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-phospho BAD Antibody (Ser155), from rabbit, purified by affinity chromatography,
物種活性
bovine, canine, human, mouse, rat
應用
immunoprecipitation (IP)
inhibition assay

western blot
Monoclonal Anti-BAD antibody produced in mouse, clone 3H8, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
proximity ligation assay

western blot
Anti-Phospho- Bad (Ser75) Antibody, from rabbit,
物種活性
human, mouse, rat
應用
western blot
Anti-BAD antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Phospho-Bad (Ser99) Antibody, from rabbit,
物種活性
human
應用
western blot