跳轉至內容
Merck

ATRX

alpha thalassemia/mental retardation syndrome X-linked

同義詞:
ATR2, JMS, MRXHF1, RAD54, RAD54L, SFM1, SHS, XH2, XNP, ZNF-HX
物種:
Human ATRX (546), Mouse Atrx (22589), Rat Atrx (246284), cow ATRX (514473), dog ATRX (480963), Domestic Rabbit ATRX (100358645), sheep ATRX (101117394), Zebrafish atrx (323299), Thale Cress ATRX (837382), naked mole-rat Atrx (101705766) ...更多
UniProtKB ID:
P46100, D3DTE2, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4
基因 ID:
  • Human(546) Summary: The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(22589) alpha thalassemia/mental retardation syndrome X-linked homolog (human)
  • Rat(246284) alpha thalassemia/mental retardation syndrome X-linked
  • cow(514473) alpha thalassemia/mental retardation syndrome X-linked
  • dog(480963) alpha thalassemia/mental retardation syndrome X-linked
  • Domestic Rabbit(100358645) alpha thalassemia/mental retardation syndrome X-linked
  • sheep(101117394) alpha thalassemia/mental retardation syndrome X-linked
  • Zebrafish(323299) alpha thalassemia/mental retardation syndrome X-linked homolog (human)
  • Thale Cress(837382) ATRX, DEXDc and helicase domain-containing protein
  • naked mole-rat(101705766) alpha thalassemia/mental retardation syndrome X-linked
  • chicken(422331) alpha thalassemia/mental retardation syndrome X-linked
  • domestic cat(101086543) alpha thalassemia/mental retardation syndrome X-linked
  • domestic guinea pig(100715238) alpha thalassemia/mental retardation syndrome X-linked

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Antibodies

產品編號
描述
物種活性
應用
HPA001906
抗ATRX 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunofluorescence
immunohistochemistry
western blot
MABE1798
Anti-ATRX Antibody, clone 39f, clone 39F, from mouse,
物種活性
human, mouse
應用
immunocytochemistry
western blot
SAB4502258
Anti-ATRX antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse
應用
ELISA
immunofluorescence
PLA0163
Rabbit anti-ATRX Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物種活性
human
應用
immunohistochemistry
immunoprecipitation (IP)
western blot