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Merck

APOE

apolipoprotein E

同義詞:
AD2, LDLCQ5, LPG
物種:
Human APOE (348), Mouse Apoe (11816), Rat Apoe (25728), naked mole-rat Apoe (101717206), domestic guinea pig Apoe (100731633), cow APOE (281004), Domestic Rabbit APOE (100009337), dog APOE (476438), domestic cat APOE (101086769)
UniProtKB ID:
P02649, B2RC15, C0JYY5, Q9P2S4
基因 ID:
  • Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
  • Mouse(11816) apolipoprotein E
  • Rat(25728) apolipoprotein E
  • naked mole-rat(101717206) apolipoprotein E
  • domestic guinea pig(100731633) apolipoprotein E
  • cow(281004) apolipoprotein E
  • Domestic Rabbit(100009337) apolipoprotein E
  • dog(476438) apolipoprotein E
  • domestic cat(101086769) apolipoprotein E

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ELISA

產品編號
描述
物種
RAB0613
Human APOE / Apolipoprotein E ELISA Kit, ,
物種
human
RAB0616
Human APOE / Apolipoprotein E 4 ELISA Kit, ,
物種
human

Antibodies

產品編號
描述
物種活性
應用
NE1004
Anti-Apolipoprotein E Mouse mAb (E6D7), liquid, clone E6D7, Calbiochem®,
物種活性
human
應用
MABN43
Anti-Apolipoprotein E4 (ApoE4) Antibody, clone 4E4, clone 4E4, from mouse,
物種活性
human
應用
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5300354
Monoclonal Anti-APOE antibody produced in mouse, clone 1H4, ascites fluid,
物種活性
human
應用
ELISA
flow cytometry
immunohistochemistry
western blot
SAB2500086
Anti-APOE antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry
western blot
SAB2701946
Anti-APOE (C-terminal) antibody produced in rabbit, ,
物種活性
human
應用
immunohistochemistry
immunoprecipitation (IP)
western blot

Proteins

產品編號
描述
物種
SRP6303
载脂蛋白E 来源于人类血浆, ≥95% (SDS-PAGE),
物種
human
A3234
Apolipoprotein E4 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder,
物種
human
SRP4696
ApoE3 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC),
物種
human
SRP4760
ApoE2 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC),
物種
human
L8039
脂蛋白，高密度 来源于人类血浆, ≥95% (SDS-PAGE), solution,
物種
human