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Merck

ALOX5AP

arachidonate 5-lipoxygenase-activating protein

同義詞:
FLAP
物種:
UniProtKB ID:
基因 ID:
  • Human(241) Summary: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(11690) arachidonate 5-lipoxygenase activating protein
  • Rat(29624) arachidonate 5-lipoxygenase activating protein
  • Horse(100034178) arachidonate 5-lipoxygenase-activating protein
  • cow(613869) arachidonate 5-lipoxygenase-activating protein
  • dog(477323) arachidonate 5-lipoxygenase-activating protein
  • domestic guinea pig(100733727) arachidonate 5-lipoxygenase-activating protein
  • chicken(770904) arachidonate 5-lipoxygenase-activating protein
  • naked mole-rat(101704126) arachidonate 5-lipoxygenase-activating protein
  • domestic cat(101090316) arachidonate 5-lipoxygenase-activating protein
  • Zebrafish(337376) arachidonate 5-lipoxygenase-activating protein

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Antibodies

產品編號
描述
物種活性
應用
Anti-FLAP/ALOX5AP (Internal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
canine, human
應用
ELISA
immunohistochemistry

western blot
Anti-ALOX5AP (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
BW B70C, >98% (HPLC), solid,
物種
human