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Merck

AK2

adenylate kinase 2

同義詞:
ADK2, AK 2
物種:
UniProtKB ID:
基因 ID:
  • Human(204) Summary: Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.[provided by RefSeq, Nov 2010]
  • Mouse(11637) adenylate kinase 2
  • Rat(24184) adenylate kinase 2
  • Zebrafish(321793) adenylate kinase 2
  • chicken(428227) adenylate kinase 2
  • dog(478145) adenylate kinase 2
  • domestic cat(101081398) adenylate kinase 2
  • sheep(101110653) adenylate kinase 2
  • cow(280716) adenylate kinase 2
  • naked mole-rat(101697619) adenylate kinase 2
  • domestic guinea pig(100714579) adenylate kinase 2

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