ADORA2A
adenosine A2a receptor
同義詞:
A2aR, ADORA2, RDC8
物種:
Human ADORA2A (135), Mouse Adora2a (11540), Rat Adora2a (25369), chicken ADORA2A (427705), naked mole-rat Adora2a (101718082), domestic guinea pig Adora2a (100135473), sheep ADORA2A (101112926), cow ADORA2A (617828), Horse ADORA2A (100034039), domestic cat ADORA2A (101080742)
UniProtKB ID:
基因 ID:
- Human(135) Summary: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
- Mouse(11540) adenosine A2a receptor
- Rat(25369) adenosine A2a receptor
- chicken(427705) adenosine A2a receptor
- naked mole-rat(101718082) adenosine A2a receptor
- domestic guinea pig(100135473) adenosine A2a receptor
- sheep(101112926) adenosine A2a receptor
- cow(617828) adenosine A2a receptor
- Horse(100034039) adenosine A2a receptor
- domestic cat(101080742) adenosine A2a receptor
- dog(403960) adenosine A2a receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Agonist
Small Molecule - Antagonist
Antibodies
產品編號
描述
物種活性
應用
抗腺苷受体A2a抗体，克隆7F6-G5-A2, clone 7F6-G5-A2, Upstate®, from mouse,
物種活性
canine, dog, human, mouse, rabbit, rat
應用
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ADORA2A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
flow cytometry
western blot
western blot
Anti-A2A Adenosine Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
canine, human
應用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-ADORA2A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物種活性
human
應用
immunohistochemistry
Anti-Adenosine A2a Receptor Antibody, Chemicon®, from rabbit,
物種活性
bovine, canine, human, pig
應用
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot