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Merck

ADAMTSL2

ADAMTS-like 2

同義詞:
GPHYSD1
物種:
UniProtKB ID:
基因 ID:
  • Human(9719) Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009]
  • Mouse(77794) ADAMTS-like 2
  • Rat(311827) ADAMTS-like 2
  • Zebrafish(100537087) ADAMTS-like 2
  • domestic guinea pig(100727597) ADAMTS-like 2
  • naked mole-rat(101716605) ADAMTS-like 2
  • cow(526780) ADAMTS-like 2
  • sheep(101111183) ADAMTS-like 2
  • dog(491276) ADAMTS-like 2
  • Horse(100066494) ADAMTS-like 2
  • domestic cat(101086513) ADAMTS-like 2
  • chicken(417147) ADAMTS-like 2

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