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Merck

[Iron and inflammation in renal diseases].

Przeglad lekarski (2014-07-16)
Ewelina Łukaszyk, Jolanta Małyszko
PMID25016784
ABSTRACT

Subclinical inflammation is one of the key mechanisms responsible for the development and progression of chronic kidney disease. It may stem from uremia, ongoing inflammation in kidney as well as latent bacterial and viral infections. Inflammation also plays a significant role in the pathogenesis of anemia of chronic disease through its impact on the iron metabolism. The paper presents the current knowledge concerning the involvement of iron in the development of anemia in chronic kidney disease, with particular reference to the role of hepcidin in systemic iron circulation.

MATERIALS
Product Number
Brand
Product Description
209309
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