A3913
L-Argininamide dihydrochloride
≥98%, suitable for ligand binding assays
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About This Item
Empirical Formula (Hill Notation):
C6H15N5O · 2HCl
CAS Number:
Molecular Weight:
246.14
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Pricing and availability is not currently available.
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Product Name
L-Argininamide dihydrochloride,
Assay
≥98%
Quality Level
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
−20°C
SMILES string
Cl.N[C@@H](CCCNC(N)=N)C(N)=O
InChI
1S/C6H15N5O.ClH/c7-4(5(8)12)2-1-3-11-6(9)10;/h4H,1-3,7H2,(H2,8,12)(H4,9,10,11);1H/t4-;/m0./s1
InChI key
BPQLYFCEVVKLLX-WCCKRBBISA-N
Application
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - STOT SE 1
Target Organs
Eyes
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Label-free aptamer-based sensors for L-argininamide by using nucleic acid minor groove binding dyes.
Zece Zhu et al.
Chemical communications (Cambridge, England), 47(11), 3192-3194 (2011-01-29)
The nucleic acid minor groove binding dyes, DAPI and Hoechst 33258, were for the first time used in label-free aptamer-based sensors for L-argininamide. The synergy binding effect results in the enhancement of fluorescence of dyes. The method for detection of
Tao Li et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 13(23), 6718-6723 (2007-05-17)
We report a novel label-free method for the investigation of the adaptive recognition of small molecules by nucleic acid aptamers using capillary electrophoresis analysis. Cocaine and argininamide were chosen as model molecules, and the two corresponding DNA aptamers were used.
Max Keller et al.
Bioorganic & medicinal chemistry, 19(9), 2859-2878 (2011-04-16)
Fluorescently labelled NPY Y(1) receptor (Y(1)R) ligands were synthesized by connecting pyrylium and cyanine dyes with the argininamide-type Y(1)R antagonist core structure by linkers, covering a wide variety in length and chemical nature, attached to the guanidine group. The most
Zhiai Xu et al.
Biosensors & bioelectronics, 26(12), 4733-4738 (2011-07-02)
Aptamers are nucleic acids that can selectively bind to a variety of targets. Aptamers usually undergo conformational transitions from a flexible or disordered structure into a rigid or ordered structure upon target-binding. This study describes a detection method for l-argininamide
G Reid Bishop et al.
Biophysical chemistry, 126(1-3), 165-175 (2006-08-18)
The thermal stability and ligand binding properties of the L-argininamide-binding DNA aptamer (5'-GATCGAAACGTAGCGCCTTCGATC-3') were studied by spectroscopic and calorimetric methods. Differential calorimetric studies showed that the uncomplexed aptamer melted in a two-state reaction with a melting temperature T(m)=50.2+/-0.2 degrees C
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