YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Synonyms:
14-3-3E, KCIP-1, MDCR, MDS
Species:
Human YWHAE (7531), Mouse Ywhae (22627), Rat Ywhae (29753), chicken YWHAE (417554), dog YWHAE (480645), domestic cat YWHAE (101101425), cow YWHAE (282125), sheep YWHAE (443300), domestic guinea pig Ywhae (100714396), naked mole-rat Ywhae (101717238)
UniProtKB ID:
Gene ID:
- Human(7531) Summary: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(22627) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
- Rat(29753) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
- chicken(417554) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
- dog(480645) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
- domestic cat(101101425) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
- cow(282125) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
- sheep(443300) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
- domestic guinea pig(100714396) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
- naked mole-rat(101717238) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-14-3-3 phospho Serine58 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, rat
Application
western blot
Anti-14-3-3 ε Antibody, CT, serum, Chemicon®,
Species Reactivity
bovine, chicken, human, mouse, rabbit, rat, sheep
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-14-3-3 Antibody (pan), from rabbit, purified by affinity chromatography,
Species Reactivity
xenopus, bovine, chicken, fish, human, mouse, porcine, rabbit, rat, sheep, zebrafish
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
Product Number
Description
Species
14-3-3 ε, untagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species