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Merck

WDR19

WD repeat domain 19

Synonyms:
ATD5, CED4, DYF-2, IFT144, NPHP13, ORF26, Oseg6, PWDMP
Species:
UniProtKB ID:
Gene ID:
  • Human(57728) Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains six WD repeats, a clathrin heavy-chain repeat, and three transmembrane domains. This gene is conserved from C. elegans to human. It may participate in androgen-regulated signaling mechanisms or in the vesicular trafficking of androgen-regulated secretory processes. Alternatively spliced transcript variants encoding distinct isoforms have been reported but the full-length nature of one of these variants has not been defined. [provided by RefSeq, Jul 2008]
  • Mouse(213081) WD repeat domain 19
  • Rat(305349) WD repeat domain 19
  • dog(479113) WD repeat domain 19
  • Zebrafish(556414) WD repeat domain 19
  • chicken(430829) WD repeat domain 19
  • domestic guinea pig(100733702) WD repeat domain 19
  • naked mole-rat(101720180) WD repeat domain 19
  • sheep(101113150) WD repeat domain 19
  • Horse(100055207) WD repeat domain 19
  • domestic cat(101084624) WD repeat domain 19
  • cow(533633) WD repeat domain 19

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