UBXN11
UBX domain protein 11
COA-1, SOC, SOCI, UBXD5
Human UBXN11 (91544), Mouse Ubxn11 (67586), Rat Ubxn11 (192207), chicken UBXN11 (419546), naked mole-rat Ubxn11 (101709741), cow UBXN11 (515112), sheep UBXN11 (101116293), domestic cat UBXN11 (101101238), dog UBXN11 (487356), domestic guinea pig Ubxn11 (100715986)
- Human(91544) Summary: This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(67586) UBX domain protein 11
- Rat(192207) UBX domain protein 11
- chicken(419546) UBX domain protein 11
- naked mole-rat(101709741) UBX domain protein 11
- cow(515112) UBX domain protein 11
- sheep(101116293) UBX domain protein 11
- domestic cat(101101238) UBX domain protein 11
- dog(487356) UBX domain protein 11
- domestic guinea pig(100715986) UBX domain protein 11
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