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Merck

U2AF2

U2 small nuclear RNA auxiliary factor 2

Synonyms:
U2AF65
Species:
Human U2AF2 (11338), Mouse U2af2 (22185), Rat U2af2 (308335), dog U2AF2 (100687048), Horse U2AF2 (100050729), cow U2AF2 (507895), sheep U2AF2 (101117445), domestic guinea pig U2af2 (100733836), naked mole-rat U2af2 (101725252), domestic cat U2AF2 (101082705)
UniProtKB ID:
P26368, Q96HC5
Gene ID:
  • Human(11338) Summary: U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]
  • Mouse(22185) U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
  • Rat(308335) U2 small nuclear RNA auxiliary factor 2
  • dog(100687048) U2 small nuclear RNA auxiliary factor 2
  • Horse(100050729) U2 small nuclear RNA auxiliary factor 2
  • cow(507895) U2 small nuclear RNA auxiliary factor 2
  • sheep(101117445) U2 small nuclear RNA auxiliary factor 2
  • domestic guinea pig(100733836) U2 small nuclear RNA auxiliary factor 2
  • naked mole-rat(101725252) U2 small nuclear RNA auxiliary factor 2
  • domestic cat(101082705) U2 small nuclear RNA auxiliary factor 2

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Antibodies

Product Number
Description
Species Reactivity
Application
U4758
Anti-U2AF65 antibody, Mouse monoclonal, clone MC3, purified from hybridoma cell culture,
Species Reactivity
xenopus, human, mouse, rat
Application
ELISA
electron microscopy
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot