TYR
tyrosinase
Synonyms:
CMM8, OCA1A, OCAIA, SHEP3
Species:
Human TYR (7299), Mouse Tyr (22173), Rat Tyr (308800), cow TYR (280951), domestic cat TYR (751100), dog TYR (403405), chicken TYR (373971), Zebrafish tyr (30207), naked mole-rat Tyr (101696609), domestic guinea pig Tyr (100713552) ...More
UniProtKB ID:
Gene ID:
- Human(7299) Summary: The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
- Mouse(22173) tyrosinase
- Rat(308800) tyrosinase
- cow(280951) tyrosinase (oculocutaneous albinism IA)
- domestic cat(751100) tyrosinase (oculocutaneous albinism IA)
- dog(403405) tyrosinase (oculocutaneous albinism IA)
- chicken(373971) tyrosinase (oculocutaneous albinism IA)
- Zebrafish(30207) tyrosinase
- naked mole-rat(101696609) tyrosinase
- domestic guinea pig(100713552) tyrosinase
- Domestic Rabbit(100008753) tyrosinase (oculocutaneous albinism IA)
- sheep(780502) tyrosinase (oculocutaneous albinism IA)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TYR antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Tyrosinase (T311) Mouse Monoclonal Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Anti-Tyrosinase antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
ANTI-TYROSINASE(C-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species