TULP3
tubby like protein 3
Synonyms:
TUBL3
Species:
Human TULP3 (7289), Mouse Tulp3 (22158), Rat Tulp3 (688749), dog TULP3 (611832), domestic cat TULP3 (101099056), chicken TULP3 (426085), cow TULP3 (516380), domestic guinea pig Tulp3 (100715001), naked mole-rat Tulp3 (101713939), sheep TULP3 (101113230)
UniProtKB ID:
Gene ID:
- Human(7289) Summary: This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009]
- Mouse(22158) tubby-like protein 3
- Rat(688749) tubby-like protein 3
- dog(611832) tubby like protein 3
- domestic cat(101099056) tubby like protein 3
- chicken(426085) tubby like protein 3
- cow(516380) tubby like protein 3
- domestic guinea pig(100715001) tubby like protein 3
- naked mole-rat(101713939) tubby like protein 3
- sheep(101113230) tubby like protein 3
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