TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
Synonyms:
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Species:
Human TNFRSF10B (8795), Mouse Tnfrsf10b (21933), Rat Tnfrsf10b (364420), chicken TNFRSF10B (373904), cow TNFRSF10B (784541), cow TNFRSF10B (282533), naked mole-rat Tnfrsf10b (101697353)
UniProtKB ID:
Gene ID:
- Human(8795) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(21933) tumor necrosis factor receptor superfamily, member 10b
- Rat(364420) tumor necrosis factor receptor superfamily, member 10b
- chicken(373904) tumor necrosis factor receptor superfamily, member 10b
- cow(784541) tumor necrosis factor receptor superfamily, member 10b
- cow(282533) tumor necrosis factor receptor superfamily, member 10b
- naked mole-rat(101697353) tumor necrosis factor receptor superfamily, member 10b
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TNFRSF10B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-DR5 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Monoclonal Anti-CD262-PE antibody produced in mouse, clone DR5-01-1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-TNFRSF10B antibody produced in mouse, clone 2D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-DR5 Antibody, CT, Chemicon®, from rabbit,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species
sTRAIL Receptor-2 (DR5) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human