RTEL1
regulator of telomere elongation helicase 1
Synonyms:
C20orf41, DKCB5, NHL, RTEL, bK3184A7.3
Species:
Human RTEL1 (51750), Mouse Rtel1 (269400), Rat Rtel1 (362288), Zebrafish rtel1 (503732), naked mole-rat Rtel1 (101711246), domestic guinea pig Rtel1 (100716322), chicken RTEL1 (419262), cow RTEL1 (505721), domestic cat RTEL1 (101095970), dog RTEL1 (485976)
UniProtKB ID:
Gene ID:
- Human(51750) Summary: In mice, inactivation of the Rtel (regulator of telomere length) gene has been shown to cause chromosome breaks, fusions, and telomere loss. In addition, Rtel is required for telomere elongation. Therefore, the mouse Rtel gene regulates chromosome stability and telomere length. This gene is the human ortholog of the mouse Rtel gene, so its protein product may play similar roles in humans. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B), generates a non-coding transcript. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
- Mouse(269400) regulator of telomere elongation helicase 1
- Rat(362288) regulator of telomere elongation helicase 1
- Zebrafish(503732) regulator of telomere elongation helicase 1
- naked mole-rat(101711246) regulator of telomere elongation helicase 1
- domestic guinea pig(100716322) regulator of telomere elongation helicase 1
- chicken(419262) regulator of telomere elongation helicase 1
- cow(505721) regulator of telomere elongation helicase 1
- domestic cat(101095970) regulator of telomere elongation helicase 1
- dog(485976) regulator of telomere elongation helicase 1
- sheep(101117606) regulator of telomere elongation helicase 1
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