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Merck

RNF213

ring finger protein 213

Synonyms:
ALO17, C17orf27, KIAA1618, MYMY2, MYSTR, NET57
Species:
Human RNF213 (57674), Mouse Rnf213 (672511), Rat Rnf213 (303735), domestic guinea pig Rnf213 (100733579), naked mole-rat Rnf213 (101725481), chicken RNF213 (422080), dog RNF213 (483355), cow RNF213 (509283), domestic cat RNF213 (101095212), sheep RNF213 (101120424)
UniProtKB ID:
Q63HN8, C9JCP4, D6RI12, F8WKS1, Q658P6, Q69YK7, Q6MZR1, Q8IWF4
Gene ID:
  • Human(57674) Summary: This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
  • Mouse(672511) ring finger protein 213
  • Rat(303735) ring finger protein 213
  • domestic guinea pig(100733579) ring finger protein 213
  • naked mole-rat(101725481) ring finger protein 213
  • chicken(422080) ring finger protein 213
  • dog(483355) ring finger protein 213
  • cow(509283) ring finger protein 213
  • domestic cat(101095212) ring finger protein 213
  • sheep(101120424) ring finger protein 213

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Antibodies

Product Number
Description
Species Reactivity
Application
ABC1391
Anti-Ring Finger Protein 213 (RNF213), from rabbit,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunoprecipitation (IP)
western blot