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Merck

PHOX2B

paired-like homeobox 2b

Synonyms:
NBLST2, NBPhox, PMX2B
Species:
Human PHOX2B (8929), Mouse Phox2b (18935), Rat Phox2b (364152), domestic guinea pig Phox2b (100718867), naked mole-rat Phox2b (101698856), chicken PHOX2B (395548), dog PHOX2B (610284), domestic cat PHOX2B (101093103), sheep PHOX2B (101110762), cow PHOX2B (783703)
UniProtKB ID:
Q99453, Q6PJD9
Gene ID:
  • Human(8929) Summary: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq, Jul 2008]
  • Mouse(18935) paired-like homeobox 2b
  • Rat(364152) paired-like homeobox 2b
  • domestic guinea pig(100718867) paired-like homeobox 2b
  • naked mole-rat(101698856) paired-like homeobox 2b
  • chicken(395548) paired-like homeobox 2b
  • dog(610284) paired-like homeobox 2b
  • domestic cat(101093103) paired-like homeobox 2b
  • sheep(101110762) paired-like homeobox 2b
  • cow(783703) paired-like homeobox 2b

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