PBX1
pre-B-cell leukemia homeobox 1
Synonyms:
Species:
Human PBX1 (5087), Mouse Pbx1 (18514), Rat Pbx1 (304947), cow PBX1 (540688), domestic guinea pig Pbx1 (100723723), naked mole-rat Pbx1 (101714961), domestic cat PBX1 (101081781), Horse PBX1 (100058426), sheep PBX1 (101108880), dog PBX1 (488669) ...More
UniProtKB ID:
Gene ID:
- Human(5087) Summary: This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
- Mouse(18514) pre B cell leukemia homeobox 1
- Rat(304947) pre-B-cell leukemia homeobox 1
- cow(540688) pre-B-cell leukemia homeobox 1
- domestic guinea pig(100723723) pre-B-cell leukemia homeobox 1
- naked mole-rat(101714961) pre-B-cell leukemia homeobox 1
- domestic cat(101081781) pre-B-cell leukemia homeobox 1
- Horse(100058426) pre-B-cell leukemia homeobox 1
- sheep(101108880) pre-B-cell leukemia homeobox 1
- dog(488669) pre-B-cell leukemia homeobox 1
- Domestic Rabbit(100341186) pre-B-cell leukemia homeobox 1
- chicken(395505) pre-B-cell leukemia homeobox 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PBX1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
western blot