NTRK1
neurotrophic tyrosine kinase, receptor, type 1
Synonyms:
MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA
Species:
Human NTRK1 (4914), Mouse Ntrk1 (18211), Rat Ntrk1 (59109), chicken NTRK1 (396337), domestic cat NTRK1 (101081603), domestic guinea pig Ntrk1 (100725325), naked mole-rat Ntrk1 (101724441), cow NTRK1 (353111), sheep NTRK1 (101109763), Domestic Rabbit NTRK1 (100354292) ...More
UniProtKB ID:
Gene ID:
- Human(4914) Summary: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
- Mouse(18211) neurotrophic tyrosine kinase, receptor, type 1
- Rat(59109) neurotrophic tyrosine kinase, receptor, type 1
- chicken(396337) neurotrophic tyrosine kinase, receptor, type 1
- domestic cat(101081603) neurotrophic tyrosine kinase, receptor, type 1
- domestic guinea pig(100725325) neurotrophic tyrosine kinase, receptor, type 1
- naked mole-rat(101724441) neurotrophic tyrosine kinase, receptor, type 1
- cow(353111) neurotrophic tyrosine kinase, receptor, type 1
- sheep(101109763) neurotrophic tyrosine kinase, receptor, type 1
- Domestic Rabbit(100354292) neurotrophic tyrosine kinase, receptor, type 1
- Horse(100064594) neurotrophic tyrosine kinase, receptor, type 1
- dog(490404) neurotrophic tyrosine kinase, receptor, type 1
- Zebrafish(30546) neurotrophic tyrosine kinase, receptor, type 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TrkA Antibody, clone 6B2, ascites fluid, clone 6B2, from mouse,
Species Reactivity
human, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TrkA Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-phospho-TrkA (pTyr490) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot