MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
Synonyms:
CLG1, HNC, MMP-8, PMNL-CL
Species:
Human MMP8 (4317), Mouse Mmp8 (17394), Rat Mmp8 (63849), domestic guinea pig Mmp8 (100724670), naked mole-rat Mmp8 (101716969), sheep MMP8 (101120601), domestic cat MMP8 (101080995), Horse MMP8 (100069005), cow MMP8 (100336575), dog MMP8 (489429)
UniProtKB ID:
Gene ID:
- Human(4317) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
- Mouse(17394) matrix metallopeptidase 8
- Rat(63849) matrix metallopeptidase 8
- domestic guinea pig(100724670) matrix metallopeptidase 8 (neutrophil collagenase)
- naked mole-rat(101716969) matrix metallopeptidase 8 (neutrophil collagenase)
- sheep(101120601) matrix metallopeptidase 8 (neutrophil collagenase)
- domestic cat(101080995) matrix metallopeptidase 8 (neutrophil collagenase)
- Horse(100069005) matrix metallopeptidase 8 (neutrophil collagenase)
- cow(100336575) matrix metallopeptidase 8 (neutrophil collagenase)
- dog(489429) matrix metallopeptidase 8 (neutrophil collagenase)
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