MCM2
minichromosome maintenance complex component 2
Synonyms:
BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
Species:
Human MCM2 (4171), Mouse Mcm2 (17216), Rat Mcm2 (312538), fruit fly Mcm2 (40973), Thale Cress MCM2 (841056), domestic guinea pig Mcm2 (100722936), naked mole-rat Mcm2 (101710978), sheep MCM2 (101116097), cow MCM2 (510120), domestic cat MCM2 (101090176) ...More
UniProtKB ID:
Gene ID:
- Human(4171) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
- Mouse(17216) minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
- Rat(312538) minichromosome maintenance complex component 2
- fruit fly(40973) Minichromosome maintenance 2
- Thale Cress(841056) minichromosome maintenance protein 2
- domestic guinea pig(100722936) minichromosome maintenance complex component 2
- naked mole-rat(101710978) minichromosome maintenance complex component 2
- sheep(101116097) minichromosome maintenance complex component 2
- cow(510120) minichromosome maintenance complex component 2
- domestic cat(101090176) minichromosome maintenance complex component 2
- dog(484622) minichromosome maintenance complex component 2
- chicken(416027) minichromosome maintenance complex component 2
- Zebrafish(192338) MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Rabbit anti-MCM2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-MCM2 antibody, Rabbit monoclonal, clone SP85, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
bovine, dog, frog, human, mouse, rat
Application
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot