LPXN
leupaxin
Synonyms:
LDPL
Species:
Human LPXN (9404), Mouse Lpxn (107321), Rat Lpxn (293783), chicken LPXN (423129), domestic cat LPXN (101097346), dog LPXN (483465), sheep LPXN (101107629), Horse LPXN (100066577), Domestic Rabbit LPXN (100008712), naked mole-rat Lpxn (101714169) ...More
UniProtKB ID:
Gene ID:
- Human(9404) Summary: The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
- Mouse(107321) leupaxin
- Rat(293783) leupaxin
- chicken(423129) leupaxin
- domestic cat(101097346) leupaxin
- dog(483465) leupaxin
- sheep(101107629) leupaxin
- Horse(100066577) leupaxin
- Domestic Rabbit(100008712) leupaxin
- naked mole-rat(101714169) leupaxin
- domestic guinea pig(100725445) leupaxin
- cow(513264) leupaxin
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