ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Synonyms:
CD11A, LFA-1, LFA1A
Species:
Human ITGAL (3683), Mouse Itgal (16408), Rat Itgal (308995), domestic cat ITGAL (101085940), dog ITGAL (489905), Horse ITGAL (100065508), sheep ITGAL (641296), cow ITGAL (281874), Domestic Rabbit ITGAL (100356927), domestic guinea pig Itgal (100713143)
UniProtKB ID:
Gene ID:
- Human(3683) Summary: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(16408) integrin alpha L
- Rat(308995) integrin, alpha L
- domestic cat(101085940) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- dog(489905) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- Horse(100065508) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- sheep(641296) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- cow(281874) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- Domestic Rabbit(100356927) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- domestic guinea pig(100713143) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- naked mole-rat(101723643) integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD11a, azide free antibody produced in mouse, clone MEM-25, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD11a antibody produced in rat, clone M17/4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
mouse
Application
flow cytometry
Monoclonal Anti-CD11a, azide free antibody produced in mouse, clone MEM-83, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry