ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Synonyms:
BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3
Species:
Human ITGA2B (3674), Mouse Itga2b (16399), Rat Itga2b (685269), domestic guinea pig Itga2b (100727374), naked mole-rat Itga2b (101714332), Horse ITGA2B (100009697), cow ITGA2B (515011), sheep ITGA2B (101115719), Zebrafish itga2b (445380), domestic cat ITGA2B (101100930)
UniProtKB ID:
Gene ID:
- Human(3674) Summary: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
- Mouse(16399) integrin alpha 2b
- Rat(685269) integrin, alpha 2B
- domestic guinea pig(100727374) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- naked mole-rat(101714332) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- Horse(100009697) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- cow(515011) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- sheep(101115719) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- Zebrafish(445380) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)
- domestic cat(101100930) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- dog(403789) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
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Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD41a antibody produced in mouse, clone HIP8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, nonhuman primates
Application
flow cytometry
Monoclonal Anti-CD41 antibody produced in mouse, clone MEM-06, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Anti-Integrin α2b (CD41) antibody, Mouse monoclonal, clone PM6/248, purified from hybridoma cell culture,
Species Reactivity
baboon, human
Application
flow cytometry
immunoprecipitation (IP)
immunoprecipitation (IP)
Anti-Integrin αIIb Mouse mAb (283.16B7), liquid, clone 283.16B7, Calbiochem®,
Species Reactivity
human
Application
Milli-Mark® Anti-CD41-FITC Antibody, clone 5B12, clone 5B12, Milli-Mark®, from mouse,
Species Reactivity
human
Application
flow cytometry
Small Molecule - Inhibitor
Product Number
Description
Species