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Merck

IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Synonyms:
AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO, ZC2HC9
Species:
UniProtKB ID:
Gene ID:
  • Human(8517) Summary: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]
  • Mouse(16151) inhibitor of kappaB kinase gamma
  • Rat(309295) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Domestic Rabbit(100328905) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic guinea pig(100722308) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • naked mole-rat(101712077) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • dog(612576) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic cat(101086544) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • cow(281855) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Zebrafish(541530) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • sheep(101107332) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

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Small Molecule - Antagonist

Product Number
Description
Species
Parthenolide, ≥98% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IKKγ Antibody, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
western blot
Anti-IKK-γ antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-IKKγ antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry

western blot

Proteins

Product Number
Description
Species
IKK-γ, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human