HSD17B6
hydroxysteroid (17-beta) dehydrogenase 6
Synonyms:
HSE, RODH, SDR9C6
Species:
Human HSD17B6 (8630), Mouse Hsd17b6 (27400), Rat Hsd17b6 (286964), cow HSD17B6 (533086), dog HSD17B6 (481118), domestic cat HSD17B6 (101088341), naked mole-rat Hsd17b6 (101699287)
UniProtKB ID:
Gene ID:
- Human(8630) Summary: The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. [provided by RefSeq, Jul 2008]
- Mouse(27400) hydroxysteroid (17-beta) dehydrogenase 6
- Rat(286964) hydroxysteroid (17-beta) dehydrogenase 6
- cow(533086) hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
- dog(481118) hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
- domestic cat(101088341) hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
- naked mole-rat(101699287) hydroxysteroid (17-beta) dehydrogenase 6
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