HDAC1
histone deacetylase 1
Synonyms:
GON-10, HD1, RPD3, RPD3L1
Species:
Human HDAC1 (3065), Mouse Hdac1 (433759), Rat Hdac1 (297893), chicken HDAC1 (373961), cow HDAC1 (404126), sheep HDAC1 (100820752), Zebrafish hdac1 (192302), domestic cat HDAC1 (101099228), naked mole-rat Hdac1 (101715102), domestic guinea pig Hdac1 (100728529)
UniProtKB ID:
Gene ID:
- Human(3065) Summary: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(433759) histone deacetylase 1
- Rat(297893) histone deacetylase 1
- chicken(373961) histone deacetylase 1
- cow(404126) histone deacetylase 1
- sheep(100820752) histone deacetylase 1
- Zebrafish(192302) histone deacetylase 1
- domestic cat(101099228) histone deacetylase 1
- naked mole-rat(101715102) histone deacetylase 1
- domestic guinea pig(100728529) histone deacetylase 1
- dog(487309) histone deacetylase 1
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Activity Assay
Product Number
Description
Species
Histone Deacetylase Assay Kit, Fluorometric, sufficient for 100 assays (96 well plates),
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HDAC1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, yeast
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-HDAC1 antibody produced in mouse, clone 3E1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-HDAC1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rat
Application
western blot
Monoclonal Anti-HDAC1 antibody produced in mouse, clone 5C11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
Anti-HDAC1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
HDAC-1 human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
Species
human
HDAC1, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species