GP1BA
glycoprotein Ib (platelet), alpha polypeptide
Synonyms:
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
Species:
Human GP1BA (2811), Mouse Gp1ba (14723), Rat Gp1ba (691992), chicken GP1BA (420059), naked mole-rat Gp1ba (101717127), domestic guinea pig Gp1ba (100717535), sheep GP1BA (101109891), cow GP1BA (504977), domestic cat GP1BA (101092307), dog GP1BA (403638)
UniProtKB ID:
Gene ID:
- Human(2811) Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]
- Mouse(14723) glycoprotein 1b, alpha polypeptide
- Rat(691992) glycoprotein Ib (platelet), alpha polypeptide
- chicken(420059) glycoprotein Ib (platelet), alpha polypeptide
- naked mole-rat(101717127) glycoprotein Ib (platelet), alpha polypeptide
- domestic guinea pig(100717535) glycoprotein Ib (platelet), alpha polypeptide
- sheep(101109891) glycoprotein Ib (platelet), alpha polypeptide
- cow(504977) glycoprotein Ib (platelet), alpha polypeptide
- domestic cat(101092307) glycoprotein Ib (platelet), alpha polypeptide
- dog(403638) glycoprotein Ib (platelet), alpha polypeptide
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD42b antibody produced in mouse, clone HIP1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, nonhuman primates
Application
flow cytometry
Anti-GP1BA antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Monoclonal Anti-GP1BA antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-CD42B antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP202, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
Milli-Mark® Anti-CD42b-PE Antibody, clone AN51, clone AN51, Milli-Mark®, from mouse,
Species Reactivity
human
Application
flow cytometry