DSC2
desmocollin 2
Synonyms:
ARVD11, CDHF2, DG2, DGII/III, DSC3
Species:
Human DSC2 (1824), Mouse Dsc2 (13506), Rat Dsc2 (291760), Domestic Rabbit DSC2 (100347153), cow DSC2 (281128), sheep DSC2 (101116192), naked mole-rat Dsc2 (101698754), domestic cat DSC2 (101085157), domestic guinea pig Dsc2 (100716280), Horse DSC2 (100065829) ...More
UniProtKB ID:
Gene ID:
- Human(1824) Summary: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Mouse(13506) desmocollin 2
- Rat(291760) desmocollin 2
- Domestic Rabbit(100347153) desmocollin 2
- cow(281128) desmocollin 2
- sheep(101116192) desmocollin 2
- naked mole-rat(101698754) desmocollin 2
- domestic cat(101085157) desmocollin 2
- domestic guinea pig(100716280) desmocollin 2
- Horse(100065829) desmocollin 2
- chicken(428527) desmocollin 2
- dog(403860) desmocollin 2
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