DOCK4
dedicator of cytokinesis 4
Synonyms:
Species:
Human DOCK4 (9732), Mouse Dock4 (238130), Horse DOCK4 (100055674), Domestic Rabbit DOCK4 (100355539), domestic guinea pig Dock4 (100716726), cow DOCK4 (534227), domestic cat DOCK4 (101082809), naked mole-rat Dock4 (101721066), chicken DOCK4 (417779), sheep DOCK4 (101113058)
UniProtKB ID:
Gene ID:
- Human(9732) Summary: This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008]
- Mouse(238130) dedicator of cytokinesis 4
- Horse(100055674) dedicator of cytokinesis 4
- Domestic Rabbit(100355539) dedicator of cytokinesis 4
- domestic guinea pig(100716726) dedicator of cytokinesis 4
- cow(534227) dedicator of cytokinesis 4
- domestic cat(101082809) dedicator of cytokinesis 4
- naked mole-rat(101721066) dedicator of cytokinesis 4
- chicken(417779) dedicator of cytokinesis 4
- sheep(101113058) dedicator of cytokinesis 4
- dog(482407) dedicator of cytokinesis 4
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