DDR1
discoidin domain receptor tyrosine kinase 1
Synonyms:
CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
Species:
Human DDR1 (780), Mouse Ddr1 (12305), Rat Ddr1 (25678), Horse DDR1 (100050861), naked mole-rat Ddr1 (101699683), domestic guinea pig Ddr1 (100725492), sheep DDR1 (101104279), cow DDR1 (534092), domestic cat DDR1 (101096728), dog DDR1 (474832)
UniProtKB ID:
Gene ID:
- Human(780) Summary: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
- Mouse(12305) discoidin domain receptor family, member 1
- Rat(25678) discoidin domain receptor tyrosine kinase 1
- Horse(100050861) discoidin domain receptor tyrosine kinase 1
- naked mole-rat(101699683) discoidin domain receptor tyrosine kinase 1
- domestic guinea pig(100725492) discoidin domain receptor tyrosine kinase 1
- sheep(101104279) discoidin domain receptor tyrosine kinase 1
- cow(534092) discoidin domain receptor tyrosine kinase 1
- domestic cat(101096728) discoidin domain receptor tyrosine kinase 1
- dog(474832) discoidin domain receptor tyrosine kinase 1
- Zebrafish(100007346) discoidin domain receptor family, member 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-DDR1 (pTyr513) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-DDR1 (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, dog, horse, human, monkey, pig
Application
immunohistochemistry
Proteins
Product Number
Description
Species
DDR1 (444-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human