CTSB
cathepsin B
Synonyms:
APPS, CPSB
Species:
Human CTSB (1508), Mouse Ctsb (13030), Rat Ctsb (64529), domestic guinea pig Ctsb (100714169), naked mole-rat Ctsb (101709008), dog CTSB (486077), Horse CTSB (100060963), domestic cat CTSB (101084873), cow CTSB (281105), sheep CTSB (780470)
UniProtKB ID:
Gene ID:
- Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13030) cathepsin B
- Rat(64529) cathepsin B
- domestic guinea pig(100714169) cathepsin B
- naked mole-rat(101709008) cathepsin B
- dog(486077) cathepsin B
- Horse(100060963) cathepsin B
- domestic cat(101084873) cathepsin B
- cow(281105) cathepsin B
- sheep(780470) cathepsin B
- chicken(396329) cathepsin B
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
Species Reactivity
bovine, human, porcine
Application
Anti-Cathepsin B antibody, Mouse monoclonal, clone CB59-4B11, purified from hybridoma cell culture,
Species Reactivity
human, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Cathepsin B, from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
Cathepsin B from human liver, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
Species
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Species
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Species
human
Cathepsin B Active human, recombinant, expressed in FreeStyle™ 293-F cells, ≥90% (SDS-PAGE),
Species
human
Small Molecule - Substrate
Product Number
Description
Species