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Merck

COPS5

COP9 signalosome subunit 5

Synonyms:
CSN5, JAB1, MOV-34, SGN5
Species:
Human COPS5 (10987), Mouse Cops5 (26754), Rat Cops5 (312916), domestic cat COPS5 (101092084), Zebrafish cops5 (393698), chicken COPS5 (426579), domestic guinea pig Cops5 (100716886), naked mole-rat Cops5 (101710038), Horse COPS5 (100051846), cow COPS5 (507179) ...More
UniProtKB ID:
Q92905, O15386, Q6AW95, Q86WQ4, Q9BQ17
Gene ID:
  • Human(10987) Summary: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
  • Mouse(26754) COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)
  • Rat(312916) COP9 signalosome subunit 5
  • domestic cat(101092084) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • Zebrafish(393698) COP9 constitutive photomorphogenic homolog subunit 5
  • chicken(426579) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • domestic guinea pig(100716886) COP9 signalosome subunit 5
  • naked mole-rat(101710038) COP9 signalosome subunit 5
  • Horse(100051846) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • cow(507179) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • sheep(101101995) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • dog(477901) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2702152
Monoclonal Anti-COPS5 antibody produced in mouse, ,
Species Reactivity
drosophila, human, mouse, rat
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot