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Merck

CIDEA

cell death-inducing DFFA-like effector a

Synonyms:
CIDE-A
Species:
Human CIDEA (1149), Mouse Cidea (12683), Rat Cidea (291541), Zebrafish cidea (100536460), domestic cat CIDEA (101096676), domestic guinea pig Cidea (100733762), naked mole-rat Cidea (101719851), cow CIDEA (527051), sheep CIDEA (101108619), dog CIDEA (490559)
UniProtKB ID:
O60543, B0YIY7, Q6UPR7
Gene ID:
  • Human(1149) Summary: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010]
  • Mouse(12683) cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
  • Rat(291541) cell death-inducing DFFA-like effector a
  • Zebrafish(100536460) cell death-inducing DFFA-like effector a
  • domestic cat(101096676) cell death-inducing DFFA-like effector a
  • domestic guinea pig(100733762) cell death-inducing DFFA-like effector a
  • naked mole-rat(101719851) cell death-inducing DFFA-like effector a
  • cow(527051) cell death-inducing DFFA-like effector a
  • sheep(101108619) cell death-inducing DFFA-like effector a
  • dog(490559) cell death-inducing DFFA-like effector a
  • chicken(768659) cell death-inducing DFFA-like effector a

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Antibodies

Product Number
Description
Species Reactivity
Application
PRS2089
Anti-CIDE-A (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
ABC350
Anti-CIDE-A Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
mouse
Application
immunofluorescence
immunohistochemistry
western blot