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Merck

CHST8

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8

Synonyms:
GALNAC4ST1, GalNAc4ST
Species:
Human CHST8 (64377), Mouse Chst8 (68947), Rat Chst8 (308511), cow CHST8 (100271926), Zebrafish chst8 (796549), Horse CHST8 (100050006), dog CHST8 (484596), domestic cat CHST8 (101090569), sheep CHST8 (101118812), chicken CHST8 (769263) ...More
UniProtKB ID:
Q9H2A9, Q9H3N2
Gene ID:
  • Human(64377) Summary: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(68947) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • Rat(308511) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • cow(100271926) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • Zebrafish(796549) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • Horse(100050006) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • dog(484596) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • domestic cat(101090569) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • sheep(101118812) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • chicken(769263) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • domestic guinea pig(100721873) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • Domestic Rabbit(100355847) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
  • naked mole-rat(101724961) carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8

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