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Merck

CBLL1

Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase

Synonyms:
HAKAI, RNF188
Species:
UniProtKB ID:
Gene ID:
  • Human(79872) Summary: This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]
  • Mouse(104836) Casitas B-lineage lymphoma-like 1
  • Rat(314028) Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
  • naked mole-rat(101701435) Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1
  • domestic guinea pig(100718115) Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1
  • chicken(417701) Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1
  • Zebrafish(394041) Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
  • dog(483262) Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1
  • sheep(101104902) Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1
  • cow(524139) Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
  • Horse(100050845) Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1
  • domestic cat(101094835) Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1

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