CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Synonyms:
ETO2, MTG16, MTGR2, ZMYND4
Species:
Human CBFA2T3 (863), Mouse Cbfa2t3 (12398), Rat Cbfa2t3 (361431), sheep CBFA2T3 (101109116), dog CBFA2T3 (489660), chicken CBFA2T3 (415846), cow CBFA2T3 (523815), domestic guinea pig Cbfa2t3 (100730951), naked mole-rat Cbfa2t3 (101709583), domestic cat CBFA2T3 (101099675)
UniProtKB ID:
Gene ID:
- Human(863) Summary: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
- Mouse(12398) core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
- Rat(361431) core-binding factor, runt domain, alpha subunit 2; translocated to, 3
- sheep(101109116) core-binding factor, runt domain, alpha subunit 2; translocated to, 3
- dog(489660) core-binding factor, runt domain, alpha subunit 2; translocated to, 3
- chicken(415846) core-binding factor, runt domain, alpha subunit 2; translocated to, 3
- cow(523815) core-binding factor, runt domain, alpha subunit 2; translocated to, 3
- domestic guinea pig(100730951) core-binding factor, runt domain, alpha subunit 2; translocated to, 3
- naked mole-rat(101709583) core-binding factor, runt domain, alpha subunit 2; translocated to, 3
- domestic cat(101099675) core-binding factor, runt domain, alpha subunit 2; translocated to, 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CBFA2T3 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rat
Application
western blot