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Merck

ATP7B

ATPase, Cu++ transporting, beta polypeptide

Synonyms:
PWD, WC1, WD, WND
Species:
Human ATP7B (540), Mouse Atp7b (11979), Rat Atp7b (24218), Zebrafish atp7b (556499), sheep ATP7B (443046), chicken ATP7B (418879), cow ATP7B (518075), domestic guinea pig Atp7b (100723125), Domestic Rabbit ATP7B (100344865), domestic cat ATP7B (101091495) ...More
UniProtKB ID:
P35670, Q16318, Q16319, Q4U3V3, Q59FJ9, Q5T7X7
Gene ID:
  • Human(540) Summary: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008]
  • Mouse(11979) ATPase, Cu++ transporting, beta polypeptide
  • Rat(24218) ATPase, Cu++ transporting, beta polypeptide
  • Zebrafish(556499) ATPase, Cu++ transporting, beta polypeptide (Wilson disease)
  • sheep(443046) ATPase, Cu++ transporting, beta polypeptide
  • chicken(418879) ATPase, Cu++ transporting, beta polypeptide
  • cow(518075) ATPase, Cu++ transporting, beta polypeptide
  • domestic guinea pig(100723125) ATPase, Cu++ transporting, beta polypeptide
  • Domestic Rabbit(100344865) ATPase, Cu++ transporting, beta polypeptide
  • domestic cat(101091495) ATPase, Cu++ transporting, beta polypeptide
  • dog(476903) ATPase, Cu++ transporting, beta polypeptide
  • naked mole-rat(101712944) ATPase, Cu++ transporting, beta polypeptide
  • Horse(100052751) ATPase, Cu++ transporting, beta polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4502224
Anti-ATP7B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
SAB1403592
Monoclonal Anti-ATP7B, (C-terminal) antibody produced in mouse, clone 3A12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
WH0000540M1
Monoclonal Anti-ATP7B antibody produced in mouse, clone 3E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot