ANPEP
alanyl (membrane) aminopeptidase
Synonyms:
APN, CD13, GP150, LAP1, P150, PEPN
Species:
Human ANPEP (290), Mouse Anpep (16790), Rat Anpep (81641), naked mole-rat Anpep (101706035), domestic guinea pig Anpep (100727522), sheep ANPEP (101104860), chicken ANPEP (395667), Domestic Rabbit ANPEP (100009167), cow ANPEP (404191), domestic cat ANPEP (493785) ...More
UniProtKB ID:
Gene ID:
- Human(290) Summary: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
- Mouse(16790) alanyl (membrane) aminopeptidase
- Rat(81641) alanyl (membrane) aminopeptidase
- naked mole-rat(101706035) alanyl (membrane) aminopeptidase
- domestic guinea pig(100727522) alanyl (membrane) aminopeptidase
- sheep(101104860) alanyl (membrane) aminopeptidase
- chicken(395667) alanyl (membrane) aminopeptidase
- Domestic Rabbit(100009167) alanyl (membrane) aminopeptidase
- cow(404191) alanyl (membrane) aminopeptidase
- domestic cat(493785) alanyl (membrane) aminopeptidase
- dog(403913) alanyl (membrane) aminopeptidase
- Horse(100050397) alanyl (membrane) aminopeptidase
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD13 antibody produced in mouse, clone WM15, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, nonhuman primates
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
immunohistochemistry
immunoprecipitation (IP)
Monoclonal Anti-CD13-APC antibody produced in mouse, clone WM15, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, nonhuman primates
Application
flow cytometry
Monoclonal Anti-CD13-PE antibody produced in mouse, clone WM15, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, nonhuman primates
Application
flow cytometry
Milli-Mark® Anti-CD13-FITC Antibody, clone WM-47, clone WM-47, Milli-Mark®, from mouse,
Species Reactivity
human
Application
flow cytometry
CD13 (SP187) Rabbit Monoclonal Antibody, ,
Species Reactivity
human
Application
immunohistochemistry