Skip to Content
Merck

AGT

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Synonyms:
ANHU, SERPINA8
Species:
Human AGT (183), Mouse Agt (11606), Rat Agt (24179), Thale Cress AGT (815822), Zebrafish agt (322485), fruit fly agt (40816), chicken AGT (421543), dog AGT (403783), domestic cat AGT (101093714), cow AGT (527114) ...More
UniProtKB ID:
P01019, Q16358, Q16359, Q96F91
Gene ID:
  • Human(183) Summary: The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
  • Mouse(11606) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Rat(24179) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Thale Cress(815822) alanine--glyoxylate aminotransferase
  • Zebrafish(322485) angiotensinogen
  • fruit fly(40816) O-6-alkylguanine-DNA alkyltransferase
  • chicken(421543) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • dog(403783) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • domestic cat(101093714) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • cow(527114) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • sheep(101119440) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • sheep(100294599) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • naked mole-rat(101717217) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • domestic guinea pig(100724950) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
RAB0010
Angiotensin II EIA Kit, for serum, plasma, culture supernatant and cell lysates,
Species
human
RAB1021
Human Angiotensinogen ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
MAB4051
Anti-Angiotensin Converting Enzyme Antibody, clone 9B9, clone 9B9, Chemicon®, from mouse,
Species Reactivity
feline, hamster, human, monkey, rat
Application
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot

Proteins

Product Number
Description
Species
A9525
Angiotensin II human, ≥93% (HPLC), powder,
Species
human
176870
Angiotensinogen, Human Plasma, Native angiotensinogen from human plasma that is cleaved by renin to generate angiotensin I. It is a part of the renin-angiotensin system that regulates blood pressure and fluid balance.,
Species
human
A9202
Angiotensin Fragment 1-7 acetate salt hydrate, ≥90% (HPLC), powder,
Species
human
A2562
Angiotensinogen from human plasma, ≥80% (SDS-PAGE), lyophilized powder,
Species
human
A9650
Angiotensin I human acetate salt hydrate, ≥90% (HPLC), powder, suitable for mammalian cell culture,
Species
human