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Merck

ACE

angiotensin I converting enzyme

Synonyms:
ACE1, CD143, DCP, DCP1, ICH, MVCD3
Species:
Human ACE (1636), Mouse Ace (11421), Rat Ace (24310), fruit fly Ace (41625), Zebrafish ace (565980), chicken ACE (419953), dog ACE (610668), Horse ACE (100064801), cow ACE (509484), sheep ACE (554335)
UniProtKB ID:
P12821, B0LPF0, B4DXI3, E7EU16, P22966, Q53YX9, Q59GY8, Q7M4L4
Gene ID:
  • Human(1636) Summary: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
  • Mouse(11421) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Rat(24310) angiotensin I converting enzyme
  • fruit fly(41625) Acetylcholine esterase
  • Zebrafish(565980) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • chicken(419953) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • dog(610668) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Horse(100064801) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • cow(509484) angiotensin I converting enzyme
  • sheep(554335) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Domestic Rabbit(100009274) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

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ELISA

Product Number
Description
Species
RAB0002
Mouse ACE  ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
MAB3502-I
Anti-Angiotensin Converting Enzyme Antibody, clone 2E2, culture supernatant, clone 2E2, from mouse,
Species Reactivity
human, rat
Application
western blot
SAB1403725
Monoclonal Anti-ACE antibody produced in mouse, clone 4B10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Y0001491
Quinapril hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Y0001503
Quinapril for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Y0000771
Perindopril for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
PHR1944
Quinapril Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1593401
Quinapril hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human

Proteins

Product Number
Description
Species
A2580
Angiotensin Converting Enzyme from porcine kidney, lyophilized powder, ≥10 units/mg protein (Bradford),
Species
AG330
PER1 (Hu), control peptide for AB5424P, ,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
H1635
N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC),
Species
mouse, human, rat
H4884
Hippuryl-His-Leu acetate salt, ,
Species
mouse, human, rat
F7131
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly, ,
Species
mouse, human, rat