AANAT
aralkylamine N-acetyltransferase
Synonyms:
DSPS, SNAT
Species:
Human AANAT (15), Mouse Aanat (11298), Rat Aanat (25120), chicken AANAT (396066), sheep AANAT (443531), domestic guinea pig Aanat (100724241), domestic cat AANAT (101098178), dog AANAT (483331), Goat AANAT (100860947), cow AANAT (281583)
UniProtKB ID:
Gene ID:
- Human(15) Summary: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(11298) arylalkylamine N-acetyltransferase
- Rat(25120) aralkylamine N-acetyltransferase
- chicken(396066) aralkylamine N-acetyltransferase
- sheep(443531) aralkylamine N-acetyltransferase
- domestic guinea pig(100724241) aralkylamine N-acetyltransferase
- domestic cat(101098178) aralkylamine N-acetyltransferase
- dog(483331) aralkylamine N-acetyltransferase
- Goat(100860947) aralkylamine N-acetyltransferase
- cow(281583) arylalkylamine N-acetyltransferase
- naked mole-rat(101713893) aralkylamine N-acetyltransferase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-Serotonin N-Acetyltransferase (N-Terminal) (pThr29) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
rat
Application
western blot
Anti-AANAT Antibody, serum, Chemicon®,
Species Reactivity
bovine, fish, human, rat, sheep
Application
western blot
Anti-Serotonin N-Acetyltransferase (C-Terminal) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
mouse, rat
Application
western blot
Anti-Serotonin N-Acetyltransferase (N-Terminal) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot