U4625

Uridine 5′-diphosphoglucose disodium salt hydrate from Saccharomyces cerevisiae

≥98%

• Synonym(s): UDP-Glc hydrate, UDPG hydrate
• Empirical Formula (Hill Notation): C₁₅H₂₂N₂Na₂O₁₇P₂ · xH₂O
• CAS Number: 28053-08-9
• Molecular Weight: 610.27 (anhydrous basis)
• MDL number: MFCD20441966
• UNSPSC Code: 41106305
• PubChem Substance ID: 24900648
• NACRES: NA.51

Properties

• biological source: Saccharomyces cerevisiae
• Assay: ≥98%
• form: powder
• storage temp.: −20°C
• SMILES string: O.[Na+].[Na+].OC[C@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C15H24N2O17P2.2Na.H2O/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;;1H2/q;2*+1;/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;;/m1.../s1
• InChI key: SRHFBUUOPANXBG-WSIJJEQHSA-L

Description

General description

Uridine diphosphate glucose (UDP-glucose) is a glycogen precursor. The transfer of glucose from UDP-glucose to growing glycogen chain is catalyzed by the enzyme glycogen synthase. The enzyme uridine diphosphate galactose-4-epimerase catalyzes the formation of UDP-glucose from UDP-galactose.

Application

Uridine 5′-diphosphoglucose disodium salt hydrate from Saccharomyces cerevisiae has been used as a substrate

• for the PpIRX10 enzyme activity from Arabidopsis thaliana
• in radiometric assay of glycosyltransferases (GTs)
• in uridine diphosphate glucose (UDP-Glc) 4-epimerase assay in Arabidopsis thaliana samples

Biochem/physiol Actions

Uridine diphosphate glucose (UDP-glucose) is an essential mediator of the cellular metabolic pathways. In yeast, the high levels of trehalose and glycogen favor increased levels of UDP-glucose.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves