T9449

D-(+)-Trehalose dihydrate

≥99% (HPLC), from starch

• Synonym(s): α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside
• Empirical Formula (Hill Notation): C₁₂H₂₂O₁₁ · 2H₂O
• CAS Number: 6138-23-4
• Molecular Weight: 378.33
• Beilstein: 5322018
• EC Number: 202-739-6
• MDL number: MFCD00071594
• UNSPSC Code: 12352201
• PubChem Substance ID: 24900594
• NACRES: NA.25

Properties

• biological source: Manihot esculenta root (Cassava)
• Assay: ≥99% (HPLC)
• form: powder
• optical activity: [α]20/D 174 to 186 °, c = 1.0% (w/v) in water
• technique(s): HPLC: suitable
• impurities: 7.3-11.6% water (Karl Fischer)
• color: white
• mp: 97-99 °C
• solubility: water: 50 mg/mL, clear, colorless to very faintly yellow
• storage temp.: room temp
• SMILES string: [H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
• InChI key: DPVHGFAJLZWDOC-PVXXTIHASA-N

Description

General description

Trehalose is a non-reducing sugar, which is formed when two glucose units are joined by a 1-1 alpha bond. This disaccharide is present naturally in several organisms like both prokaryotes and eukaryotes.

Application

D-(+)-Trehalose dihydrate has been used:

• in trehalose test to stabilize pharmaceutical products
• as a component of trehalose/sucrose solution for the preparation of J-aggregates
• in the preparation of simulated honey sugar cocktail (SHSC) to study its effect on chemical and thermal stability of proteins

Biochem/physiol Actions

Trehalose is a 1-alpha (disaccharide) sugar that supports plants and animals to withstand extended periods of desiccation. Trehalose acts as a cryoprotectant in a variety of cell freezing media. It serves as a primary carbon source and as a compatible solute accumulated as a response to osmotic stress and heat shock.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves